Researchers at the Shenzhen Institutes of Advanced Technology have developed two novel small-molecule systems, PRINCE and Little Prince, aimed at enhancing the control of CRISPR editing.
This work, led by Dr. Wang Yu, was published in the journal Science Translational Medicine on July 3, 2026.
The introduction of these systems marks a significant advancement in the therapeutic applications of CRISPR technology, potentially allowing for more precise gene editing in living organisms.